HURTHLE CELL ADENOMAS AND CARCINOMAS OF ΤΗΕ THYROID GLAND
Abstract
We reviewed 20 cases of Hurthle cell tumors of the thyroid from a total of 1518 patients for various thyroid disorders, during the period from 1978 to 1992. There were 18 adenomas and 2 carcinomas amongst the 14 women and 6 men, mean average of 50 years old. The preoperative diagnosis was cold nodule in 13 cases from which 11 Hurthle cell adenomas and 2 carcinomas apeared. Preoperative diagnosis οf multinodular goiter was made in 5 cases οf which all were histologicaly adenomas. Two HC adenomas were dίagnosed preoperatively by F.N.A. Biopsy in patient with nodular goiter. Greece is an endemic country and so we consider that surgery is deffinetely recommended for cases of these tumors.
References
Thyroid neoplasia in "Endocrinology". Leslie Degroot, Saunders; co: 1989.
Thyroid carcinoma in "Endocrin and Metabol Clinics of ΝΑ". Sept. 1990.
Mazzaferri Εl, Young RL: Papillary thyroid carcinoma. Α 10 year follow up report of the impact of therapy in 576 patients. Am J Med 70:511 581, 1981.
Αηδοvόπουλος Α, Βαλτής Δ, Γραμματικος Φ: Σχέσεις του κλινικώς μονήρους όζου προς το καρκίνωμα του θυρεοειδούς αδένος. Γαληνός 1971;13, 5, 690-701.
Μαvωλάκης Π, Κρασσάς Γ, Φαλτσής Σ: Η διερεύνηση του ψυχρού οζου του σπινθηρογραφήματος με Β Υπερηχογραφική μέθοδο. ΧΙ Παν. Συν. Χειρ., Πρακτικά, Τόμος 1:777-779, 1978.
Harsoulis Ρ, Leontsini Μ, Economou Α, Gerasimidis Τ, Sbarounis C: Br J Surg 1986 Vol 73, June,4612-464.
Bondeson L, Azavedo Ε et al: Nuclear DNA content and behavior of Oxyphil Thyroid Tumors. Cancer 58: 672-75, 1986.
Gundry SR et al: Total Thyroidectomy of Hurthle cell neoplasms of the Thyroid. Ann Surg 1983: 118:529-32.
Flint Α, Davenport R, et al: Cytophotometric measurements of Hurthle cell tumors of the thyroid. Cancer 61: 110-113, 1988.
Johnson Τ, Lioyd R et al: Hurthke cell tumors. Αn Immunohistochemical study. Cancer 59:107-112, 1987.
Campora RG, Zapatero ΑΗ: Hurthle cell and mitochondrion rich tumors. Α clinicopathologic study. Cancer 57: 1154-63, 1986.
Κεραμιδάς ΓΔ: Παθολογία του καρκίνου. Τα νεοπλάσματα των ενδοκρινών αδένων. "ΘΕΑΓΕΝΕΙΟ" 1992.
Follicular and Hurthle Cell Carcinoma of the Thyroid Endocrinology and Metabolism. Clin of Ν Am: Vol 19 Νον;1990;577-589 .
Ryan JJ, Hay ID, et al: Flow Cytometric DNA Measurements in Benign and Malignant Hurthle Cell Tumors of the Thyroid. World J Surg: 12, 482-487, 1988.